Oprah does everything in a big way. She affects book sales in ways that make publishers drool. She gains a lot of weight then she loses a lot of weight. She can make someone go from just living in a household to being a household name. She certainly has a pop culture Midas touch of sorts so recently she lent that power to none other than the folks at Twitter.
Of course her impact has its supporters and detractors. Hitwise reports some pretty strong numbers around the posting of her first tweet last Friday. Interestingly, the chart below may also reflect the promotion leading up to the event itself more than anything else.